Subacute necrotizing encephalomyelopathy (Leigh syndrome) in pediatric patients: a retrospective study
نویسندگان
چکیده
منابع مشابه
MR findings in patients with subacute necrotizing encephalomyelopathy (Leigh syndrome): correlation with biochemical defect.
MR studies were correlated with biochemical results in nine children who presented with lactic acidosis and/or abnormal MR findings in the basal ganglia. Neurologic development was delayed in all nine children. Seven of these patients were diagnosed as having subacute necrotizing encephalomyelopathy (SNE, or Leigh syndrome) on the basis of history, clinical findings, and biochemical studies; of...
متن کاملSubacute necrotising encephalomyelopathy (Leigh’s disease; Leigh syndrome)
Like so many complex and incurable neurological disorders, the disease first described in this journal in 1951 by (Archibald) Denis Leigh (1915–1998; figure 1) as ‘Subacute Necrotising Encephalomyelopathy’ (SNE) remained for many years a rare and intriguing enigma, of interest mainly to paediatric neurologists and neuropathologists. The more recent history of this disorder, now designated Leigh...
متن کاملImpact commentaries. Subacute necrotising encephalomyelopathy (Leigh's disease; Leigh syndrome).
Like so many complex and incurable neurological disorders, the disease first described in this journal in 1951 by (Archibald) Denis Leigh (1915–1998; figure 1) as ‘Subacute Necrotising Encephalomyelopathy’ (SNE) remained for many years a rare and intriguing enigma, of interest mainly to paediatric neurologists and neuropathologists. The more recent history of this disorder, now designated Leigh...
متن کاملSubacute necrotizing encephalomyelopathy in an infant.
K.H., a boy, aged 7 months 3 weeks, was admitted to King's College Hospital on April 22, 1947. Birth had been normal (birth weight 63 lb.) as also was development until six weeks before admission. The infant was vaccinated at the age of 2 months. He was breast-fed entirely for six weeks, then complementary feeding was begun. The baby's behaviour was normal until six weeks before admission when ...
متن کاملMR of Leigh's disease (subacute necrotizing encephalomyelopathy).
MR images of three patients with Leigh's disease (subacute necrotizing encephalomyelopathy) were compared with CT findings. In all patients typical lesions in the basal ganglia were identified with both MR and CT. In two patients MR permitted identification of additional lesions not detected with CT. In one patient progression of MR abnormalities over a 4-month period correlated well with clini...
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ژورنال
عنوان ژورنال: International Journal of Research in Medical Sciences
سال: 2015
ISSN: 2320-6071
DOI: 10.18203/2320-6012.ijrms20151138